Characterization of M1 Selective and Brain Penetrant [11 C] PIPE 307 PET Radiotracer in Cynomolgus Monkeys

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Austin Chen, Amy Llopis Amenta, Chris Baccei, Giulia Boscutti, Benjamin P. Burke, Christophe Plisson, Christine Sandiego, Lisa Wells, Daniel Lorrain

Presented at Brain & Brain PET 2022

PIPE-791, a potent brain-penetrant selective LPA1 antagonist, reduces neuroinflammation in vivo 

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Geraldine C Edu, Michael M Poon, Ariana O Lorenzana, Alexander Broadhead, Chris Baccei, Jeff Roppe, Thomas Schrader, Lino Valdez, Yifeng Xiong, Austin Chen, and Daniel S Lorrain

Presented at Neuroscience 2022

Discovery of remyelination therapeutics that overcome the effects of inflammatory macrophages on oligodendrocyte formation

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Kym I Lorrain, Michael M Poon, Alexander Broadhead, Geraldine Edu, Jonah R Chan, Austin Chen, Daniel S Lorrain

Presented at Neuroscience 2022

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